Vogue featured Dr. Babak Azizzadeh in its January 20, 2026 article, “Dermatologists on the PDRN Skincare Actually Worth Buying,” a comprehensive expert-led guide examining the surge in popularity of PDRN-based skin-care products.
The article explores the science behind PDRN (polydeoxyribonucleotide)—a DNA-derived ingredient long used in medical and wound-healing settings—and why it is now gaining traction in both in-office treatments and topical skincare. Dr. Azizzadeh explains that PDRN has been most extensively studied for its role in tissue repair, where it is believed to activate adenosine A2A receptors to calm inflammation, stimulate new blood vessel formation, and support collagen renewal and skin regeneration.
In the context of consumer skincare, Dr. Azizzadeh emphasizes that topical PDRN products are most effective when paired with delivery-enhancing treatments, such as microneedling or laser-assisted channels, which allow the ingredient to reach deeper layers of the skin. He also cautions that while early results are promising, the research on topical formulations is still evolving and outcomes should be approached with realistic expectations.
Throughout the feature, Dr. Azizzadeh provides expert insight on how PDRN can improve skin hydration, texture, and overall health—while distinguishing evidence-based benefits from marketing hype. His inclusion underscores his role as a trusted authority in translating advanced regenerative science into safe, patient-focused aesthetic care.
👉 Read the full article on VOGUE.com:
https://www.vogue.com/article/best-pdrn-serum